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酮好致力於生酮飲食的研究與推廣

【影片】胰島素阻抗新觀點

(影片字幕為外掛,若未出現,可參考字幕設定教學)

胰島素阻抗是第二型糖尿病的主要原因,而過去對於胰島素阻抗的觀念是錯誤的,導致目前治療方針的錯誤。

這場演講中,Dr. Jason Fung提出造成胰島素阻抗的新理論,認為第二型糖尿病患者產生胰島素阻抗的原因,並不是因為鎖和鑰匙理論中的機制被破壞,造成胰島素作用下降,而是單純因為身體裡的糖太多,細胞無法有效利用過剩的糖,只能轉化為脂肪而形成脂肪肝,過量的果糖攝取以及澱粉造成的脂肪肝,才是導致胰島素阻抗的核心原因。

注射胰島素只是將過多的糖硬塞進細胞,並沒有解決糖過多的問題,而且是錯誤的治療方式,要清除身體裡過多糖的方法,最有效的就是低醣飲食與間歇性斷食。

Dr. Jason Fung最後語重心長地提到,糖尿病造成的諸多臨床症狀如腦心血管疾病、腎病變、視網膜病變等其實都是可以逆轉的。過去我們都用了錯誤的理論來治療糖尿病。飲食造成的疾病就需要從飲食著手,而這樣的改變,我們隨時隨地都可以做得到。改變,就從自己以及告訴身邊的人開始做起。而那個沒有糖尿病、沒有病痛的世界,就從今天開始!

【參考資料】

  1. Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II study http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(09)60619-X.pdf

  2. Surgical treatment of obesity and its effect on diabetes: 10-y follow-up.

    Am J Clin Nutr. 1992 Feb;55(2 Suppl):582S-585S. https://www.ncbi.nlm.nih.gov/pubmed/1733132

  3. Bariatric Surgery versus Intensive Medical Therapy in Obese Patients with Diabetes

    N Engl J Med 2012; 366:1567-1576

    http://www.nejm.org/doi/pdf/10.1056/NEJMoa1200225

  4. Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized controlled trial.

    JAMA. 2008 Jan 23;299(3):316-23

    http://jamanetwork.com/journals/jama/fullarticle/1149302

  5. Rapid improvement in diabetes after gastric bypass surgery: is it the diet or surgery?

    Diabetes Care. 2013 Sep;36(9):2741-7

    http://care.diabetesjournals.org/content/36/9/2741.long

  6. Type 2 diabetes: etiology and reversibility.

    Diabetes Care. 2013 Apr;36(4):1047-55

    http://care.diabetesjournals.org/content/36/4/1047.long

  7. Effects of Intensive Glucose Lowering in Type 2 Diabetes

    N Engl J Med 2008; 358:2545-2559

    http://www.nejm.org/doi/pdf/10.1056/NEJMoa0802743

  8. Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes

    N Engl J Med 2008; 358:2560-2572

    http://www.nejm.org/doi/pdf/10.1056/NEJMoa0802987

  9. Intensive glucose control and macrovascular outcomes in type 2 diabetes.

    Diabetologia. 2009 Nov;52(11):2288-98

    https://link.springer.com/content/pdf/10.1007%2Fs00125-009-1470-0.pdf

  10. Acarbose Treatment and the Risk of Cardiovascular Disease and Hypertension in Patients With Impaired Glucose Tolerance

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    http://jamanetwork.com/journals/jama/fullarticle/196993

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